Invasiveness and the microbiome: gut microbial community dynamics in an invasive-native vertebrate system

Biological invasions are one of the major threats to biodiversity worldwide, due to the many impacts and rapid spread of

invasive alien species (IAS). However, the exact mechanisms underlying invasiveness remain poorly understood. I

hypothesise that metagenomic plasticity may be involved in invasions, i.e. IAS may be able to quickly acclimate and adapt to

their new environment and oust native species thanks to the higher dynamism of their microbial community structure and/or

gene expression patterns. I will study microbiome dynamics in two phylogenetically-close mammals: a successful invader

(grey squirrel, Sciurus carolinensis) and a native species ousted by the former (red squirrel, Sciurus vulgaris), investigating

the diverse interplay among their gut microbiome, parasite infection, dietary flexibility and behaviour (individual personality). I

will employ an observational approach in a natural experimental setting, comparing variation in the microbiome-phenome

dynamics of the two species at both the individual-level (across seasons) and population-level (along a natural-urban

gradient). InvasOME will help disclose the mechanisms behind invasiveness and rapid adaptation of IAS, offering useful

insights that may prove relevant for the prevention and management of biological invasions. This project is highly

multidisciplinary and perfectly integrates several disciplines part of my skill set (invasion ecology, parasitology and

behavioural ecology) with state-of-the-art metagenomics in which I will receive advanced training by the proposed host, who

has a relevant experience and an innovative and interdisciplinary approach to these fields. I designed this project also to

enhance my transferable skills, making the most of the host institution initiatives. I am thus confident that InvasOME will both

open an under-explored line of research and at the same time greatly enhance my potential, helping my transition to an

independent researcher position.