SINGLE CELL DISCOVERIES BV

Projekt → Revealing plasticity of developmental cell fate decisions by single-cell RNA labelling Every time an egg is fertilised, the cellular diversity of an animal must be rebuilt from scratch. Therefore, a central question… Beitrag ansehen → Projekt → Mapping the axolotl brain and its regeneration The Axolotl is an extraordinary model system to study regeneration in tetrapods. Remarkably, the axolotl is able to regenerate pa… Beitrag ansehen → Projekt → Endothelial immunosuppressive mystery genes for alternative immunotherapy: artificial intelligence-driven target discovery and lipid nanoparticle/RNA-based target validation Compared to my previous Advanced ERC grants, this proposal is fundamentally different not only concerning its topic but also rega… Beitrag ansehen → Projekt → Uncovering the role and regulation of 3D DNA-RNA nuclear dynamics in controlling cell fate decisions At the onset of mammalian life, the first lineage specification decision is made where embryonic cells opt to become either part… Beitrag ansehen → Projekt → The hidden majority: high-resolution imaging and genomics of the most ecologically important microbial eukaryotes in the ocean How have eukaryotes evolved into the vast diversity we see nowadays? At present this simple question remains a mystery, mostly du… Beitrag ansehen → Projekt → Transcriptional adaptation during vertebrate development at the single-cell level The development of a multicellular organism requires the precise control of gene expression in space and time so that cells adopt… Beitrag ansehen →