HBOX THERAPIES GMBH

Projekt → Response-aware molecular subtyping of ulcerative colitis for patient stratification via interpretable machine learning Ulcerative colitis (UC) is a heterogeneous inflammatory disease with diverse molecular features and variable responses to biologi… Beitrag ansehen → Projekt → Polyclonal anti-tumor immunity by engineered human T cells Adoptive T cell therapies are a new class of living drugs, achieving durable results in a subset of patients with aggressive mali… Beitrag ansehen → Projekt → Cancer cell plasticity on targeted therapy Novel cancer molecular-targeted therapies allow to significantly prolong the survival of cancer patients. However, the inevitable… Beitrag ansehen → Projekt → Deciphering the radiobiology of targeted radionuclide therapy: from subcellular to intra-tumoural analyses Background and unmet need Targeted radionuclide therapies (TRTs) are a promising modality to treat patients with metastasized can… Beitrag ansehen → Projekt → The brain erythropoietin cycle as driver of adaptive neuroplasticity via functional hypoxia Cognitive disability and decline play key roles in neuropsychiatric conditions but lack effective therapies. Erythropoietin (EPO)… Beitrag ansehen → Projekt → Dissecting the neutrophil-cancer cell interactome in the metastatic bone niche Bone is one of the most common organs for solid tumour metastasis. 75% of patients with late-stage breast cancer develop recurren… Beitrag ansehen →