Force-Dependent Behaviour of Non-Standard DNA Structures and their Uses in Artificial DNA Machines and in Genetic Regulation

Projekt → Elucidating the role of biomolecular condensation in meiotic DNA double-strand break formation Meiosis universally relies on the formation of DNA double-strand breaks (DSB) to initiate a genome-wide recombination program tha… Beitrag ansehen → Projekt → Optimization of surface multi-channel electrode arrays and motor unit extraction in underrepresented populations The motor unit (MU) represents the final common pathway consisting of the motor neuron and all the muscle fibres it innervates. F… Beitrag ansehen → Projekt → Sonio: Deep-Learning for Detection and Diagnostic of Prenatal Malformations 1 child out of 33 is born with a congenital malformation in developed countries, leading to mortality & disability which impact t… Beitrag ansehen → Projekt → From CO2 and Nitrogen fixation to the delivery of therapeutic enzymes: Silicified DNA origami as artificial microcompartments All life is dependent on enzymatic reactions and functional enzyme cascades have been evolutionary optimized. Yet, introducing “f… Beitrag ansehen → Projekt → Kinetic Limits of Many-Body Classical Systems This project studies the transition between dynamical laws governing the physical world at different scales. Our focus will be on… Beitrag ansehen → Projekt → Mechanisms of cellular response to errors in mitosis: a new, non-genetic approach to an old question One of the holy grails in cancer biology is to understand how genomic instability, a hallmark source of mutagenesis, arises. Howe… Beitrag ansehen →