INSTITUT PASTEUR

Forschungsprojekte

• Exploring the Prokaryotic-Eukaryotic Conservation of Antiviral immunity: from bacterial immune systems to novel antiviral drugs Bacteria have evolved multiple lines of defense against their viruses, bacteriophages. Such weapons include r…
• From cell shape to organism shape: the cellular basis for the evolutionary origin of animal morphogenesis "My work concerns a critical question: How did the cellular mechanisms underpinning animal morphogenesis firs…
• In situ genetic perturbation of gut bacteria with engineered phage vectors and CRISPR Humans live in a symbiotic relationship with trillions of microorganisms that inhabit our bodies and play an…
• Processing-in-memory architectures and programming libraries for bioinformatics algorithms Low cost, high throughput DNA and RNA sequencing (HTS) data is now the main workforce for various genomics an…
• SEROLOGICAL TESTING AND TREATMENT FOR P. VIVAX: FROM A CLUSTER-RANDOMISED TRIAL IN ETHIOPIA AND MADAGASCAR TO A MOBILE-TECHNOLOGY SUPPORTED INTERVENTION P. vivax is considered the most difficult human malaria to eliminate because of the inability of conventional…
• Characterization of the Mobility and Evolution of Non-Transmissible Plasmids Bacteria are extraordinarily adaptive organisms spread all over the globe and making up about half of the cel…
• Mapping genetic suppression interaction networks in DNA break repair disorders DNA double-strand breaks (DSBs) occur frequently during a cell’s lifetime and constitute the most cytotoxic D…
• Impact of Reactive Oxygen Species produced by their sand fly vector on Leishmania sexual hybrid formation By transmitting hundreds of pathogens causing important human mortality and morbidity, vector insects are a m…
• Molecular mechanisms underlying Zika virus transmission by Aedes aegypti mosquitoes The public health response to emerging mosquito-borne viral diseases is often inefficient, because the causat…
• Digital Innovations and Diagnostics for Infectious Diseases in Africa The DI-DIDA project's overall objective is to tackle poverty-related infectious diseases in sub-Saharan Afric…
• Stem and niche cell dynamics in normal and pathological conditions Coherent tissue growth and repair require an interplay between stem cells and their local and systemic enviro…
• Study of membrane lipid composition and alpha-synuclein spreading Neurodegenerative pathologies (NDs), including Parkinson’s disease, represent a huge burden worldwide from a…