FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH

Forschungsprojekte

• Mechanism of vertebrate sperm-egg recognition and fusion The life of every sexually reproducing being can be traced back to a singular event: the fusion of sperm and…
• Cohesin Therapeutics. Precision medicine for treating STAG2 mutated cancers The cohesin gene STAG2 has emerged as a new tumour suppressor frequently mutated in bladder cancer, Ewing sar…
• Deciphering immune evasion mechanisms of metastatic cancer cells using CRISPRa-inducible reporters Most cancer patients are resistant to immunotherapies, especially patients with liver and bone metastases. Th…
• Deconstructing Intestinal Immune Tolerance The intestinal tract is the main site of nutrient absorption and faces constant exposure to complex environme…
• Guard-driven immunity against pathogens Successful pathogens use virulence factors to inhibit immune defenses. To counteract this, host guard protein…